2018 was the year of the dog, so, as it comes to a close, we are releasing a chromosome-length, de novo genome assembly for the Golden Retriever dog breed! The assembly, created exclusively using short Illumina reads, was done in collaboration with the Broad Institute.
This genome assembly has contig N50 equal to 133Kb and scaffold N50 equal to 59Mb, the latter determined by the size distribution of the dog’s 39 chromosomes. Since the best current dog reference, CanFam3.1 (NCBI accession GCF_000002285.3; contig N50: 267Kb; scaffold N50: 63Mb), comes from a Boxer (Lindblad-Toh et al., 2005), the new genome should facilitate inter-breed comparisons. A dotplot comparing the assemblies is below.
Note a 10Mb inversion with respect to CanFam3.1 chromosome 9. This inversion is shared by the dingo genome assembly and hence likely represents the ancestral form.
Happy New Year everyone! Don't stop retrievin' in 2019!